Review
Immunogenetics of Hashimoto's thyroiditis
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Correspondence: Dimitry A Chistiakov dimitry.chistiakov@eudoramail.com
Laboratory of Aquatic Ecology, Katholieke Universiteit Leuven, Ch. De Beriotstraat 32, B-3000 Leuven, Belgium
Journal of Autoimmune Diseases 2005, 2:1 doi:10.1186/1740-2557-2-1
Published: 11 March 2005Abstract
Hashimoto's thyroiditis (HT) is an organ-specific T-cell mediated disease. It is a complex disease, with a strong genetic component. To date, significant progress has been made towards the identification and functional characterization of HT susceptibility genes. In this review, we will summarize the recent advances in our understanding of the genetic input to the pathogenesis of HT.