Table 1 |
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|
Selected studies exploring the relation of multiple sclerosis with human herpes virus-6 |
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|
Material used |
Method followed |
Relation to MS |
Year of publication |
|
|
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|
Brain tissue |
Viral DNA-PCR, immunohistochemistry |
Positive |
1995[44] |
|
Viral DNA-PCR |
Negative |
1996[49] |
|
|
Viral DNA-PCR, immunohistochemistry |
Positive |
1999[47] |
|
|
Immunohistochemistry |
Positive |
2000[58] |
|
|
Viral DNA-PCR |
Positive |
2000[59] |
|
|
Viral DNA-PCR, immunohistochemistry |
Positive |
2003[60] |
|
|
Viral DNA-PCR |
Uncertain |
2003[48] |
|
|
CSF |
Viral DNA-PCR |
Negative |
1999[50] |
|
Viral DNA-PCR, antibodies titer |
Negative |
2000[51] |
|
|
Viral DNA-PCR, antibodies titer |
Positive |
2002[52] |
|
|
Serum |
Viral DNA-PCR |
Negative |
1999[50] |
|
Viral DNA-PCR, antibodies titer |
Positive |
2000[52] |
|
|
Viral DNA-PCR |
Positive |
2000[53] |
|
|
Viral DNA-PCR |
Positive |
2001[54] |
|
|
Viral DNA-PCR |
Negative |
2002[55] |
|
|
Viral DNA-PCR, antibodies titer |
Positive |
2003[56] |
|
|
Peripheral blood mononuclear cells |
Viral DNA-PCR |
Negative |
2000[51] |
|
Viral DNA-PCR |
Positive |
2000[53] |
|
|
Viral DNA-PCR |
Negative |
2000[57] |
|
|
Viral DNA-PCR |
Positive |
2001[54] |
|
|
Viral DNA-PCR |
Positive |
2002[55] |
|
|
Viral DNA-PCR |
Positive |
2003[56] |
|
|
|
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Grigoriadis and Hadjigeorgiou Journal of Autoimmune Diseases 2006 3:1 doi:10.1186/1740-2557-3-1 |
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