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Patients' characteristics. |
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| Parameters |
Patients with liver diseases* (n = 423) |
Patients with coincidence of AIH and any kind of liver disorder (n = 24)** |
Patients with AIH/overlap syndromes (n = 10) |
Patients with coincidence of AIH and other liver disease (n = 14) |
Patients with AIH (n = 43) |
|
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| Gender (F/M) |
231/192 |
12/12 |
5/5 |
7/7 |
33/10 |
| Age mean ± SD (years) |
51.6 ± 22.7 |
54.9 ± 18.6 |
49.6 ± 21.6 |
57.7 ± 15.5 |
52.3 ± 15.7 |
| Serum globulin or IgG above normal (pos/neg; pos = score ≥ 1) |
202/221 |
17/7 |
7/3 |
10/4 |
34/9 |
| Alcohol abuse (>60 g/day: yes/no) |
98/325 |
3/21 |
0/10 |
3/11 |
1/42 |
| Drug use (yes/no) |
25/398 |
0/24 |
0/10 |
0/14 |
1/42 |
| Other autoimmune diseases (yes/no) |
24/399 |
7/17 |
5/5 |
2/12 |
18/25 |
| ANA or SMA or anti-LKM (pos/neg) (positive titre ≥ 1:40) |
335/88 |
23/1 |
9/1 |
14/0 |
43/0 |
| AMA (pos/neg) |
49/374 |
4/20 |
4/6 |
0/14 |
0/43 |
| Histology (pos/neg) (pos = score > 0, neg = score ≤ 0) |
58/365 |
13/11 |
3/7 |
10/4 |
35/8 |
| Total histologic score ± SD |
-4 ± 3.3 |
0.38 ± 3.72 |
-2.1 ± 4.4 |
2.14 ± 1.7 |
2.73 ± 1.98 |
| Median (range) |
-5 (-11 to +5) |
1 (-8 to +4) |
0 (-8 to +4) |
3 (0 to +4) |
3 (-3 to +5) |
|
Abbreviations are same as in text. *Excluding AIH patients (n = 43) and patients with coincidence of AIH and any kind of liver disorder (n = 24); **Means the coexistence of AIH with any kind of other liver disease; M = male; F = female. | |||||
Papamichalis et al. Journal of Autoimmune Diseases 2007 4:3 doi:10.1186/1740-2557-4-3 |
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